Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 11/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559678 | 0.87 | MEN1 (0.51) | MEN1KMT2ACA2BACE1CCR5 | |
| SCHEMBL17595993 | 0.85 | MEN1 (0.45) | MEN1KMT2ACA2BACE1BACE2 | |
| SCHEMBL17595995 | 0.85 | MEN1 (0.45) | MEN1KMT2ACA2BACE1BACE2 | |
| SCHEMBL17595996 | 0.85 | MEN1 (0.45) | MEN1KMT2ACA2BACE1BACE2 | |
| SCHEMBL18921021 | 0.84 | MEN1 (0.44) | MEN1KMT2ACA2BACE1BACE2 | |
| SCHEMBL18921022 | 0.84 | MEN1 (0.44) | MEN1KMT2ACA2BACE1BACE2 | |
| SCHEMBL28236293 | 0.77 | HDAC8 (0.44) | MEN1KMT2ACA2BACE1BACE2 | |
| SCHEMBL28236294 | 0.77 | HDAC8 (0.44) | MEN1KMT2ACA2BACE1BACE2 | |
| SCHEMBL29558722 | 0.75 | CCR5 (0.41) | BACE1CCR5 | |
| SCHEMBL17595568 | 0.75 | MEN1 (0.41) | MEN1KMT2ACA2BACE1PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114732916-B | Targeted delivery of tertiary amine-containing drug substances | 西雅图基因公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-114732916-A | Targeted delivery of tertiary amine-containing drug substances | 西雅图基因公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-107108694-B | Targeted delivery of tertiary amine-containing drug substances | 西雅图基因公司 | 2022-05-03 | — | — | CN | disclosed |