Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15087053 | 1.00 | RAC1 (1.00) | RAC1KMT2AMEN1NPY5RRAD52 | |
| SCHEMBL29414239 | 1.00 | RAC1 (1.00) | RAC1KMT2AMEN1NPY5RRAD52 | |
| SCHEMBL29920432 | 0.88 | RAC1 (0.79) | RAC1KMT2AMEN1NPY5RRAD52 | |
| SCHEMBL20966313 | 0.88 | RAC1 (0.79) | RAC1KMT2AMEN1NPY5RRAD52 | |
| SCHEMBL20966317 | 0.83 | RAC1 (0.71) | RAC1KMT2AMEN1NPY5RL3MBTL1 | |
| SCHEMBL29920372 | 0.83 | RAC1 (0.71) | RAC1KMT2AMEN1NPY5RL3MBTL1 | |
| SCHEMBL20945473 | 0.82 | RAC1 (0.69) | RAC1KMT2AMEN1NPY5RL3MBTL1 | |
| SCHEMBL20966330 | 0.80 | RAC1 (0.67) | RAC1KMT2AMEN1NPY5RL3MBTL1 | |
| SCHEMBL20966319 | 0.79 | RAC1 (0.65) | RAC1NPY5RRAD52L3MBTL1MAPT | |
| SCHEMBL29920699 | 0.79 | RAC1 (0.65) | RAC1NPY5RRAD52L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250249014-A1 | A COMBINATION FOR TREATING A RETINAL DISEASE | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2025-08-07 | — | — | US | disclosed |
| CN-119080753-A | HinK inhibitor and preparation method and application thereof | 国科大杭州高等研究院 | 2024-12-06 | — | — | CN | disclosed |
| WO-2024171957-A1 | TRANSPLANTATION OF PITUITARY HORMONE-PRODUCING CELLS | 国立大学法人東海国立大学機構 | 2024-08-22 | — | — | WO | disclosed |
| CN-117618439-A | Method for inhibiting porcine epidemic diarrhea virus in-vitro infection by EHop-016 and application thereof | 河南牧业经济学院 | 2024-03-01 | — | — | CN | disclosed |
| EP-4240339-A1 | COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION | Fred Hutchinson Cancer Center (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2023054395-A1 | CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME | 住友ファーマ株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023054396-A1 | METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS | 住友化学株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023277135-A1 | METHOD FOR PRODUCING CELLS CONSTITUTING NASAL EPITHELIUM, AND CELL POPULATION INCLUDING CELLS CONSTITUTING NASAL EPITHELIUM OR PROGENITOR CELLS THEREOF | 住友化学株式会社 | 2023-01-05 | — | — | WO | disclosed |
| WO-2022098776-A1 | COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2022-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250249014-A1 | A COMBINATION FOR TREATING A RETINAL DISEASE | ALDH1A2, NR2E3, EYA3 | RAC1 250/4885KMT2A 4558/4885MEN1 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.