Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223999 | 1.00 | CES2 (0.46) | CES2CES1TPMTTAS1R3TAS1R1 | |
| SCHEMBL2293145 | 0.85 | CES2 (0.55) | CES2CES1HCAR1 | |
| SCHEMBL114867 | 0.85 | CES2 (0.62) | CES2CES1HCAR1GRM5 | |
| SCHEMBL3358922 | 0.83 | TPMT (0.55) | CES2CES1TPMTHCAR1 | |
| SCHEMBL93282 | 0.83 | TPMT (0.62) | CES2CES1TPMTHCAR1 | |
| SCHEMBL29454778 | 0.82 | TPMT (0.70) | CES2CES1TPMTTAS1R3TAS1R1 | |
| SCHEMBL572200 | 0.82 | TPMT (0.70) | CES2CES1TPMTTAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL28632192 | 0.80 | TPMT (0.59) | TPMTHCAR1 | |
| SCHEMBL9631667 | 0.80 | PARP1 (0.50) | CES2CES1TPMTTAS1R3TAS1R1 | |
| SCHEMBL30463182 | 0.80 | PARP1 (0.50) | CES2CES1TPMTTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561563-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024067566-A1 | SATURATED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PHARMACEUTICAL USE THEREOF | 苏州阿尔脉生物科技有限公司 | 2024-04-04 | — | — | WO | disclosed |
| CN-117800894-A | Saturated cyclic derivative, pharmaceutical composition containing same and medical application of saturated cyclic derivative | 苏州阿尔脉生物科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2024026129-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| EP-4240352-A1 | T-TYPE CALCIUM CHANNEL MODULATORS AND METHODS OF USE THEREOF | Praxis Precision Medicines, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099207-A1 | T-TYPE CALCIUM CHANNEL MODULATORS AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2022-05-12 | — | — | WO | disclosed |