SCHEMBL2293145

SCHEMBL2293145

O=C(Cl)c1cc(F)cc(C(=O)Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.55
CES1 P23141 6/20 0.55
HCAR1 Q9BXC0 1/20 0.44
HCAR2 Q8TDS4 1/20 0.38
PARP1 P09874 1/20 0.38
ALDH1A1 P00352 3/20 0.36
ALOX15 P16050 1/20 0.36
HDAC1 Q13547 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CA1 P00915 2/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
CA2 P00918 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
ERN1 O75460 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114867 0.94 CES2 (0.62) CES2CES1HCAR1HCAR2PARP1
SCHEMBL5223999 0.85 CES2 (0.46) CES2CES1HCAR1
SCHEMBL29558481 0.85 CES2 (0.46) CES2CES1HCAR1
SCHEMBL38576 0.85 ALDH1A1 (0.40) CES2CES1HCAR1ALDH1A1ALOX15
SCHEMBL15935951 0.84 CES2 (0.44) CES2CES1HCAR1HCAR2PARP1
SCHEMBL5225361 0.84 CES2 (0.44) CES2CES1HCAR1HCAR2PARP1
SCHEMBL31327392 0.84 CES2 (0.44) CES2CES1HCAR1HCAR2PARP1
SCHEMBL30821970 0.83 KDM4E (0.50) CES2CES1ALDH1A1CA1CA12
Hydrochloric Acid SCHEMBL18918955 0.82 ALDH1A1 (0.39) CES2CES1ALDH1A1ALOX15CA1
SCHEMBL679313 0.80 CES2 (0.52) CES2CES1HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112126057-B Binaphthyl organic polymer hole transport material and synthetic method and application thereof 天津理工大学 2021-04-13 CN claimed
CN-112126057-A Binaphthyl organic polymer hole transport material and synthetic method and application thereof 天津理工大学 2020-12-25 CN claimed
US-7060332-B2 Liquid crystal display with alignment film of polyphenylenphthalamide-based material and method for fabricating the same LG.PHILIPS LCD CO., LTD. (KR) 2006-06-13 US claimed
US-20020182346-A1 Liquid crystal display with alignment film of polyphenylenphthalamide-based material and method for fabricating the same LG DISPLAY CO., LTD. (KR) 2002-12-05 US claimed
WO-2025128334-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
WO-2025128332-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
WO-2025128333-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
US-20250189892-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
US-20250188311-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
US-20250188312-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
CN-112126057-A Binaphthyl organic polymer hole transport material and synthetic method and application thereof 天津理工大学 2020-12-25 CN disclosed
CN-107983343-B Decarbonylation chlorination catalyst and preparation method and application thereof 上海化工研究院有限公司 2020-12-11 CN disclosed
US-20140042082-A1 CHLORINE RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR 2014-02-13 US disclosed
US-20110203990-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME MURPHY ANDREW PATRICK 2011-08-25 US disclosed
US-7806275-B2 Chlorine resistant polyamides and membranes made from the same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE INTERIOR, THE BUREAU OF RECLAMATION (US) 2010-10-05 US disclosed
WO-2008140840-A9 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME US GOV INTERIOR (US) 2009-03-12 WO disclosed
WO-2008140840-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME GOVERNMENT OF THE USA AS REPRESENTED BY THE DEPARTMENT OF THE INTERIOR - BUREAU OF RECLAMATION (US) 2008-11-20 WO disclosed
US-20080277333-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME SEPARATION SYSTEMS TECHNOLOGY INC. 2008-11-13 US disclosed
US-7060332-B2 Liquid crystal display with alignment film of polyphenylenphthalamide-based material and method for fabricating the same LG.PHILIPS LCD CO., LTD. (KR) 2006-06-13 US disclosed
US-20020182346-A1 Liquid crystal display with alignment film of polyphenylenphthalamide-based material and method for fabricating the same LG DISPLAY CO., LTD. (KR) 2002-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110203990-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME CLIC1, CLIC4, CLCN2 CES2 9/4885CES1 572/4885HCAR1 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.