Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6113938 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL90647 | 0.92 | ALDH1A1 (0.40) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL29558779 | 0.92 | ALDH1A1 (0.40) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8768025 | 0.92 | ALDH1A1 (0.40) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13366897 | 0.87 | ALDH1A1 (0.36) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL61324 | 0.86 | SLC6A2 (0.40) | HTTSMN1; SMN2SLC6A2SLC6A4KCNH2 | |
| SCHEMBL61260 | 0.79 | PARG (0.49) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL20303047 | 0.62 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL55488 | 0.62 | TDP2 (0.40) | KMT2AMEN1MAPTNPSR1POLB | |
| SCHEMBL29902416 | 0.57 | PARG (0.50) | KDM4EALDH1A1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314663-B | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | 多格伍德药品公司 | 2022-05-13 | — | — | CN | disclosed |