Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.34 |
| ▸ | CDK2 | P24941 | 6/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.34 |
| ▸ | ATM | Q13315 | 3/20 | 0.33 |
| ▸ | CCND3 | P30281 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541779 | 1.00 | CDK4 (0.35) | CDK4CSF1RCDK6CCNA2CDK2 | |
| SCHEMBL21541746 | 0.93 | CDK4 (0.37) | CDK4CSF1RCDK6CCNA2CDK2 | |
| SCHEMBL21541733 | 0.93 | CDK4 (0.37) | CDK4CSF1RCDK6CCNA2CDK2 | |
| SCHEMBL21541766 | 0.92 | EML4 (0.34) | CDK4CSF1RCDK6CCNA2CDK2 | |
| SCHEMBL27132009 | 0.92 | EML4 (0.34) | CDK4CSF1RCDK6CCNA2CDK2 | |
| SCHEMBL21541749 | 0.92 | CSF1R (0.37) | CDK4CSF1RCDK6CCNA2CDK2 | |
| SCHEMBL21541716 | 0.92 | CDK4 (0.34) | CDK4CSF1RCDK6CCNA2CDK2 | |
| SCHEMBL21541857 | 0.91 | CDK4 (0.35) | CDK4CSF1RCDK6CCNA2CDK2 | |
| SCHEMBL21541800 | 0.91 | MELK (0.35) | ATMATRMTORPIK3CAMET | |
| SCHEMBL21541763 | 0.90 | CCNA2 (0.34) | CDK4CCNA2CDK2CCNA1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-A9 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2022-04-20 | — | — | EP | disclosed |