Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24946530 | 1.00 | CYP19A1 (0.36) | CYP19A1HTR2AHTR2CHTR2B | |
| SCHEMBL24947197 | 0.86 | CYP19A1 (0.36) | CYP19A1HTR2AHTR2CHTR2B | |
| SCHEMBL29559313 | 0.86 | CYP19A1 (0.36) | CYP19A1HTR2AHTR2CHTR2B | |
| SCHEMBL24946531 | 0.83 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL29558914 | 0.83 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL19631289 | 0.79 | IMPDH2 (0.34) | CYP19A1 | |
| SCHEMBL2122013 | 0.74 | UPP1 (0.33) | CYP19A1 | |
| SCHEMBL21625577 | 0.74 | HTR2A (0.37) | CYP19A1HTR2AHTR2CHTR2B | |
| SCHEMBL24946532 | 0.73 | ALDH1A1 (0.40) | CYP19A1 | |
| SCHEMBL28731831 | 0.73 | KDM4E (0.39) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023000834-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| CN-113480534-B | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 广州必贝特医药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |