Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771284 | 0.79 | — | — | |
| SCHEMBL304934 | 0.79 | — | — | |
| SCHEMBL1695588 | 0.77 | — | — | |
| SCHEMBL35748 | 0.75 | — | — | |
| SCHEMBL7079749 | 0.75 | — | — | |
| SCHEMBL9190446 | 0.75 | — | — | |
| SCHEMBL31514259 | 0.75 | HSD17B10 (0.30) | HSD17B10TDP1 | |
| SCHEMBL975737 | 0.75 | — | — | |
| SCHEMBL14252091 | 0.73 | — | — | |
| SCHEMBL11814781 | 0.73 | ALDH1A1 (0.30) | ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234516-A1 | NOVEL ADDUCTS AND CURABLE COMPOSITIONS USING SAME | LOCTITE (R&D) LIMITED (IE) | 2010-09-16 | — | — | US | disclosed |
| US-7759435-B2 | Adducts and curable compositions using same | LOCTITE (R&D) LIMITED (IE) | 2010-07-20 | — | — | US | disclosed |
| US-7750094-B2 | Adducts and curable compositions using same | LOCTITE (R&D) LIMITED (IE) | 2010-07-06 | — | — | US | disclosed |
| US-20090234079-A1 | Glycidylamino-capped adducts of siloxanes are curing agents for thermosettable benzoxazines, epoxides, episulfides; improved toughness | LOCTILE (R&D) LIMITED (IE) | 2009-09-17 | — | — | US | disclosed |
| US-20080076886-A1 | Backbones of polyethers, perfluorinated polyethers, polydimethylsiloxanes and hydroxy terminated polybutadienes coupled to phenyl, biphenyl, bisphenol A, bisphenol F, bisphenol S, bisphenol E, allyl, alkyl, alkenyl, carboxy, N-carbamoyl, cyclic amides, epoxy and a thermosetting component; toughening | LOCTITE (R&D) LIMITED | 2008-03-27 | — | — | US | disclosed |