Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17842342 | 1.00 | KMT2A (0.72) | KMT2AHSD17B14MEN1RAB9ANPC1 | |
| Methane SCHEMBL27540707 | 0.98 | KMT2A (0.70) | KMT2AHSD17B14MEN1RAB9ANPC1 | |
| SCHEMBL398165 | 0.84 | KMT2A (1.00) | KMT2AHSD17B14MEN1RAB9ANPC1 | |
| SCHEMBL29373829 | 0.84 | KMT2A (1.00) | KMT2AHSD17B14MEN1RAB9ANPC1 | |
| SCHEMBL13600090 | 0.83 | KMT2A (0.81) | KMT2AHSD17B14RAB9ANPC1CES1 | |
| SCHEMBL29571462 | 0.83 | KMT2A (0.75) | KMT2AHSD17B14MEN1RAB9ANPC1 | |
| SCHEMBL2485773 | 0.83 | KMT2A (0.75) | KMT2AHSD17B14MEN1RAB9ANPC1 | |
| SCHEMBL20412777 | 0.82 | KMT2A (0.54) | KMT2AHSD17B14MEN1RAB9ANPC1 | |
| SCHEMBL28015961 | 0.82 | KMT2A (0.96) | KMT2AHSD17B14MEN1RAB9ANPC1 | |
| SCHEMBL28005707 | 0.82 | KMT2A (0.96) | KMT2AHSD17B14MEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220296581-A1 | Immunomodulation by IAP Inhibitors | NOVARTIS AG (CH) | 2022-09-22 | — | — | US | disclosed |
| US-11382905-B2 | Immunomodulation by IAP inhibitors | NOVARTIS AG (CH) | 2022-07-12 | — | — | US | disclosed |
| EP-3983401-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | Arkuda Therapeutics (US) | 2022-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220296581-A1 | Immunomodulation by IAP Inhibitors | BIRC2, BIRC3, BIRC5 | KMT2A 3118/4885HSD17B14 4818/4885MEN1 949/4885 |
| US-11382905-B2 | Immunomodulation by IAP inhibitors | BIRC2, BIRC3, BIRC5 | KMT2A 3118/4885HSD17B14 4818/4885MEN1 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.