Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670985 | 0.90 | GRM5 (0.42) | VCPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7552481 | 0.85 | APP (0.52) | MEN1KMT2AMAPTALDH1A1APP | |
| SCHEMBL29561909 | 0.80 | APP (0.42) | MEN1KMT2AMAPTALDH1A1APP | |
| SCHEMBL29187593 | 0.80 | APP (0.42) | MEN1KMT2AMAPTALDH1A1APP | |
| SCHEMBL29561314 | 0.80 | APP (0.42) | MEN1KMT2AMAPTAPPPAM | |
| SCHEMBL29561344 | 0.79 | MEN1 (0.45) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL29187603 | 0.77 | HPGD (0.56) | VCPMAPTALDH1A1PAMLMNA | |
| SCHEMBL2831992 | 0.75 | APP (0.67) | VCPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15014207 | 0.75 | APP (0.67) | VCPMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10091202 | 0.75 | APP (0.67) | VCPMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724110-B | Preparation method and application of 4-heteroatom-3, 4,5 substituted isoxazole compound | 香港科技大学深圳研究院 | 2022-04-26 | — | — | CN | disclosed |