Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560906 | 0.90 | VCP (0.44) | GRM5ALDH1A1CA12CA2CA9 | |
| SCHEMBL24296678 | 0.78 | ALDH1A1 (0.48) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL25767482 | 0.76 | ACHE (0.40) | ALDH1A1CYP2A6CA2CA9CA1 | |
| SCHEMBL9445826 | 0.74 | GRM5 (0.64) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL4457730 | 0.74 | GRM5 (0.64) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL9715647 | 0.72 | GRM5 (0.61) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL7552481 | 0.71 | APP (0.52) | GRM5ALDH1A1CA12CA2CA9 | |
| SCHEMBL28355119 | 0.71 | ALDH1A1 (0.50) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL10858546 | 0.70 | ACHE (0.44) | ALDH1A1CYP2A6CA2CA9CA1 | |
| SCHEMBL1119058 | 0.70 | ACHE (0.44) | ALDH1A1CYP2A6CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080170-B1 | INSERTION POLYNORBORNENE-BASED THERMOSET RESINS | TRANSFERT PLUS SEC (CA) | 2020-02-05 | — | — | EP | disclosed |