Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777421 | 1.00 | PRCP (0.60) | PRCPRECQLTSHRNPSR1GAA | |
| SCHEMBL1738261 | 0.80 | PRCP (0.83) | PRCPRECQLTSHRNPSR1GAA | |
| SCHEMBL3865487 | 0.77 | PRCP (0.97) | PRCPRECQLTSHRNPSR1GAA | |
| SCHEMBL28083503 | 0.77 | PRCP (0.90) | PRCPRECQLTSHRNPSR1GAA | |
| SCHEMBL9600234 | 0.76 | PRCP (0.57) | PRCPKMT2A | |
| SCHEMBL31374586 | 0.76 | PRCP (0.57) | PRCPKMT2A | |
| SCHEMBL31374588 | 0.76 | PRCP (0.57) | PRCPKMT2A | |
| SCHEMBL24017043 | 0.76 | PRCP (0.70) | PRCPRECQLTSHRNPSR1GAA | |
| SCHEMBL30368634 | 0.76 | PRCP (0.70) | PRCPRECQLTSHRNPSR1GAA | |
| SCHEMBL16799768 | 0.76 | PRCP (0.70) | PRCPRECQLTSHRNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113950477-B | Granulin precursor modulators and methods of use thereof | 阿库达医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-3983401-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | Arkuda Therapeutics (US) | 2022-04-20 | — | — | EP | disclosed |