SCHEMBL31374586

SCHEMBL31374586

c1ccc2c(c1)CC1CCNC21

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.57
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
KMT2A Q03164 1/20 0.40
HTR2C P28335 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9600234 1.00 PRCP (0.57) PRCPCHRNB2CHRNA4GRIN2DGRIN3B
SCHEMBL31374588 1.00 PRCP (0.57) PRCPCHRNB2CHRNA4GRIN2DGRIN3B
SCHEMBL3073561 0.89 PRCP (0.63) PRCPCHRNB2CHRNA4GRIN2DGRIN3B
SCHEMBL11931707 0.89 PRCP (0.63) PRCPCHRNB2CHRNA4GRIN2DGRIN3B
SCHEMBL1724425 0.83 PRCP (0.70) PRCPCHRNB2CHRNA4
SCHEMBL1738261 0.77 PRCP (0.83) PRCPHTR2C
SCHEMBL29560964 0.76 PRCP (0.60) PRCPKMT2A
SCHEMBL22777421 0.76 PRCP (0.60) PRCPKMT2A
SCHEMBL18322101 0.75 PNMT (0.41) HTR2C
SCHEMBL3136750 0.75 CHRNB2 (0.40) CHRNB2CHRNA4HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025021140-A1 COMPOUND FOR DEGRADING TARGET PROTEIN 海南先声再明医药股份有限公司 2025-01-30 WO disclosed