Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.71 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.71 |
| ▸ | RXRB | P28702 | 7/20 | 0.48 |
| ▸ | RXRA | P19793 | 6/20 | 0.48 |
| ▸ | RXRG | P48443 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26230931 | 0.87 | GABRA1 (0.55) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL30490541 | 0.85 | GABRA1 (0.58) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL25355961 | 0.85 | GABRA1 (0.58) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL18268 | 0.84 | GABRA1 (1.00) | GABRA1GABRB2RXRBRXRARXRG | |
| Methyl Alcohol SCHEMBL21467316 | 0.84 | GABRA1 (0.52) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL4572745 | 0.84 | GABRA1 (0.58) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL29771943 | 0.82 | ABL1 (0.60) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL28857358 | 0.82 | ABL1 (0.60) | GABRA1GABRB2RXRBRXRARXRG | |
| Hydrochloric Acid SCHEMBL7075850 | 0.81 | GABRA1 (0.94) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL14973413 | 0.81 | GABRA1 (0.94) | GABRA1GABRB2RXRBRXRARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315883-B | Dibenzofuran phenol IVB metal complex and preparation method thereof, catalyst system and olefin polymerization method | 万华化学集团股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-112358498-B | Tetraaryloxy IVB group binuclear metal complex and preparation and application thereof | 万华化学集团股份有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-112142775-B | Phenolphenanthroline IVB group metal complex and preparation and application thereof | 万华化学集团股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-114315883-A | Dibenzofuran phenol IVB group metal complex, preparation method thereof, catalyst system and olefin polymerization method | 万华化学集团股份有限公司 | 2022-04-12 | — | — | CN | disclosed |