SCHEMBL4572745

SCHEMBL4572745

CC(C)(C)c1cc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)cc(C(C)(C)C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.58
GABRB2 P47870 1/20 0.58
RXRB P28702 7/20 0.54
RXRA P19793 6/20 0.54
RXRG P48443 3/20 0.54
KDM4E B2RXH2 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
POLB P06746 1/20 0.46
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39
KIF11 P52732 2/20 0.39
HTR1D P28221 1/20 0.39
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26230931 0.97 GABRA1 (0.55) GABRA1GABRB2RXRBRXRARXRG
SCHEMBL4526927 0.91 RXRB (0.65) GABRA1GABRB2RXRBRXRARXRG
SCHEMBL414084 0.91 RXRB (0.65) GABRA1GABRB2RXRBRXRARXRG
SCHEMBL93161 0.89 GABRA1 (0.69) GABRA1GABRB2RXRBRXRARXRG
SCHEMBL29252866 0.88 GABRA1 (0.55) GABRA1GABRB2RXRBRXRARXRG
SCHEMBL29252907 0.88 GABRA1 (0.55) GABRA1GABRB2RXRBRXRARXRG
Methyl Alcohol SCHEMBL21467316 0.87 GABRA1 (0.52) GABRA1GABRB2RXRBRXRARXRG
SCHEMBL10394690 0.85 GABRA1 (0.65) GABRA1GABRB2RXRBRXRARXRG
SCHEMBL10415675 0.85 GABRA1 (0.65) GABRA1GABRB2RXRBRXRARXRG
SCHEMBL23915436 0.84 GABRA1 (0.44) GABRA1GABRB2RXRBRXRARXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806474-A Method for recovering 2,6-di-tert-butylphenol and 2,2',6,6' -tetra-tert-butyl-4,4 ' -biphenol 烟台新秀新材料有限公司 2023-03-17 CN claimed
US-12600691-B2 Process for producing mixed alcohols from purge stream containing octene DOW GLOBAL TECHNOLOGIES LLC (US) 2026-04-14 US disclosed
US-12595221-B1 Hydroformylation processes DOW TECHNOLOGY INVESTMENTS LLC (US) 2026-04-07 US disclosed
US-12595339-B2 Preparation of organosilicon compounds with aldehyde functionality DOW SILICONES CORPORATION (US) 2026-04-07 US disclosed
US-20250353968-A1 Preparation of AMINO-FUNCTIONAL Organosilicon Compounds DOW SILICONES CORPORATION 2025-11-20 US disclosed
US-20250257169-A1 COMPOSITION, URETHANE PREPOLYMER, AND RELATED METHODS AND USES DOW SILICONES CORP (US) 2025-08-14 US disclosed
EP-4413009-B1 PREPARATION OF AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-06 EP disclosed
US-20250215162-A1 PREPARATION OF POLYETHER-FUNCTIONAL ORGANOSILICON COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-03 US disclosed
US-12331012-B2 Organic catalyst for non-aqueous aldol condensation DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-17 US disclosed
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS DOW SILICONES CORP (US) 2025-05-01 US disclosed
EP-1695141-A1 METHOD FOR CHEMICAL SENSITIZATION FOR PHOTOTHERMOGRAPHIC USE EASTMAN KODAK COMPANY (US) 2006-08-30 EP disclosed
WO-2005062121-A1 METHOD FOR CHEMICAL SENSITIZATION FOR PHOTOTHERMOGRAPHIC USE EASTMAN KODAK COMPANY (US) 2005-07-07 WO disclosed
WO-2005040914-A1 THERMALLY DEVELOPABLE IMAGING MATERIALS HAVING BACKSIDE STABILIZERS EASTMAN KODAK COMPANY (US) 2005-05-06 WO disclosed
WO-2005040915-A1 THERMALLY DEVELOPABLE IMAGING MATERIALS HAVING BACKSIDE STABILIZERS EASTMAN KODAK COMPANY (US) 2005-05-06 WO disclosed
CN-1339721-A New bipolar organic light sensitive body XIANLI NEW TECHNOLOGY CO LTD T (CN) 2002-03-13 CN disclosed
EP-0856504-B1 Process for producing 3,3',5,5'-tetra-t-butylbiphenol HONSHU CHEMICAL IND (JP) 2001-11-07 EP disclosed
EP-0280938-B1 Antioxidant aromatic fluorophosphites ETHYL CORP (US) 1994-06-15 EP disclosed
US-4958034-A DISCOLORATION INHIBITION; REACTION OF OLEFIN AND MALEIC ANHYDRIDE IN ARYLFLUOROPHOSPHITE PRESENCE ETHYL CORPORATION (US) 1990-09-18 US disclosed
US-4177156-A SPECIALTY OILS FOR TRANSFORMERS RHONE-POULENC INDUSTRIES (FR) 1979-12-04 US disclosed
US-4119555-A COOLANTS FOR TRANSFORMERS RHONE-POULENC INDUSTRIES (FR) 1978-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600691-B2 Process for producing mixed alcohols from purge stream containing octene ADH1C, OR10J3, ADH1A GABRA1 4519/4885GABRB2 3917/4885RXRB 4413/4885
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS VCL, FANCF, MMS19 GABRA1 2186/4885GABRB2 4224/4885RXRB 960/4885
US-12331012-B2 Organic catalyst for non-aqueous aldol condensation C9, ENO1, C1S GABRA1 4735/4885GABRB2 4700/4885RXRB 4431/4885
US-20250215162-A1 PREPARATION OF POLYETHER-FUNCTIONAL ORGANOSILICON COMPOUNDS SI, HPD, PHF2 GABRA1 3013/4885GABRB2 3390/4885RXRB 4249/4885
US-12595339-B2 Preparation of organosilicon compounds with aldehyde functionality EPCAM, MCM6, OR10J3 GABRA1 2852/4885GABRB2 2202/4885RXRB 2717/4885
US-12595221-B1 Hydroformylation processes HSF1, ADH1A, HAO2 GABRA1 3097/4885GABRB2 3358/4885RXRB 4203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.