Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561463 | 0.86 | MAPT (0.67) | MAPTPOLBPKMPGRKMT2A | |
| SCHEMBL29562114 | 0.84 | MAPT (0.66) | MAPTPOLBPKMPGRALDH1A1 | |
| SCHEMBL29561514 | 0.83 | MAPT (0.65) | MAPTPOLBPKMPGRKMT2A | |
| SCHEMBL29561791 | 0.82 | MAPT (0.62) | MAPTHTR6PGR | |
| SCHEMBL29561784 | 0.82 | MAPT (0.62) | MAPTPOLBPGRKMT2APLAU | |
| SCHEMBL29562337 | 0.82 | MAPT (0.58) | MAPTPOLBPKMKMT2AMEN1 | |
| SCHEMBL29562119 | 0.81 | MAPT (0.64) | MAPTPOLBPKMPGRKMT2A | |
| SCHEMBL29562355 | 0.81 | MAPT (0.63) | MAPTPKMKMT2AKEAP1MEN1 | |
| SCHEMBL29562518 | 0.81 | MAPT (0.63) | MAPTPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL17779177 | 0.80 | TSHR (0.63) | MAPTPOLBPKMHTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |