Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561129 | 0.86 | MAPT (0.65) | MAPTPGRALDH1A1TP53POLB | |
| SCHEMBL29562114 | 0.85 | MAPT (0.66) | MAPTPGRALDH1A1TP53POLB | |
| SCHEMBL29561514 | 0.84 | MAPT (0.65) | MAPTPGRALDH1A1TP53POLB | |
| SCHEMBL29561791 | 0.83 | MAPT (0.62) | MAPTPGR | |
| SCHEMBL29561784 | 0.83 | MAPT (0.62) | MAPTPGRTP53POLBKMT2A | |
| SCHEMBL29562119 | 0.82 | MAPT (0.64) | MAPTPGRALDH1A1TP53POLB | |
| SCHEMBL29562518 | 0.82 | MAPT (0.63) | MAPTALDH1A1TP53PKMKMT2A | |
| SCHEMBL29562355 | 0.82 | MAPT (0.63) | MAPTALDH1A1TP53PKMKMT2A | |
| SCHEMBL29561797 | 0.81 | MAPT (0.61) | MAPTPGRALDH1A1TP53POLB | |
| SCHEMBL29561330 | 0.81 | MAPT (0.61) | MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |