Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 7/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562355 | 0.93 | MAPT (0.63) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL14048137 | 0.84 | KMT2A (0.57) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL29561286 | 0.84 | MAPT (0.55) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL14048146 | 0.83 | KMT2A (0.56) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL14048147 | 0.82 | KMT2A (0.55) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL29561463 | 0.82 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL29562114 | 0.82 | MAPT (0.66) | MAPTALDH1A1LMNACYP3A4PKM | |
| SCHEMBL29561514 | 0.81 | MAPT (0.65) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5230414 | 0.81 | MAPT (0.76) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL29561129 | 0.81 | MAPT (0.65) | MAPTALDH1A1KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |