Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
| ▸ | CMA1 | P23946 | 16/20 | 0.57 |
| ▸ | CTRC | Q99895 | 2/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560799 | 1.00 | F2 (0.62) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL9815839 | 0.95 | F2 (0.62) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL9618661 | 0.91 | CMA1 (0.58) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL29445785 | 0.91 | F2 (0.53) | F2PRSS1CMA1CTRC | |
| SCHEMBL7371676 | 0.90 | F2 (0.64) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL11013694 | 0.90 | F2 (0.60) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL11013687 | 0.90 | F2 (0.60) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL9601186 | 0.90 | F2 (0.56) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL22962005 | 0.88 | F2 (0.58) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL29934589 | 0.86 | OPRM1 (0.58) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073587-B | Synthesis process for synthesizing bivalirudin by semi-continuous liquid phase synthesis | 厦门胜泽泰医药科技有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-115073587-A | Synthesis process of semicontinuous liquid phase synthesis bivalirudin | 厦门胜泽泰医药科技有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-112062835-B | Preparation method of bivalirudin | 扬子江药业集团四川海蓉药业有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-115073587-B | Synthesis process for synthesizing bivalirudin by semi-continuous liquid phase synthesis | 厦门胜泽泰医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-117088966-A | Synthesis method of bivalirudin impurity | 江苏诺泰澳赛诺生物制药股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-115073587-A | Synthesis process of semicontinuous liquid phase synthesis bivalirudin | 厦门胜泽泰医药科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-112062835-B | Preparation method of bivalirudin | 扬子江药业集团四川海蓉药业有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-112062835-B | Preparation method of bivalirudin | 扬子江药业集团四川海蓉药业有限公司 | 2022-04-26 | — | — | CN | disclosed |