Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.64 |
| ▸ | PLG | P00747 | 2/20 | 0.58 |
| ▸ | CMA1 | P23946 | 15/20 | 0.51 |
| ▸ | CTRC | Q99895 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366341 | 0.93 | F2 (0.56) | F2PRSS1PLGCMA1CTRC | |
| SCHEMBL9815839 | 0.90 | F2 (0.62) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL29562010 | 0.90 | F2 (0.62) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL29560799 | 0.90 | F2 (0.62) | F2PRSS1CMA1CTRCACE | |
| Hydrochloric Acid SCHEMBL7416216 | 0.90 | F2 (0.54) | F2PRSS1PLGACE | |
| Hydrochloric Acid SCHEMBL7296655 | 0.89 | F2 (0.59) | F2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL7409436 | 0.89 | F2 (0.59) | F2PRSS1PLGACE | |
| Efegatran SCHEMBL635674 | 0.89 | F2 (0.58) | F2PRSS1PLG | |
| SCHEMBL11013687 | 0.88 | F2 (0.60) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL11013694 | 0.88 | F2 (0.60) | F2PRSS1CMA1CTRCACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675899-B1 | NOVEL INHIBITORS OF FACTOR Xa | CORVAS INT INC (US) | 1999-03-17 | — | — | EP | disclosed |
| US-5883077-A | PEPTIDES ALDEHYDE ANALOGUES | CORVAS INTERNATIONAL, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| US-5739112-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0675899-A4 | NOVEL INHIBITORS OF FACTOR Xa. | CORVAS INT INC (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0675899-A1 | NOVEL INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994013693-A1 | NOVEL INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1994-06-23 | — | — | WO | disclosed |