Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 19/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562648 | 0.85 | USP30 (0.65) | USP30 | |
| SCHEMBL19385369 | 0.80 | USP30 (1.00) | USP30 | |
| SCHEMBL29562302 | 0.78 | USP30 (0.68) | USP30 | |
| SCHEMBL29562251 | 0.76 | USP30 (0.44) | USP30 | |
| SCHEMBL29562882 | 0.76 | USP30 (0.70) | USP30DRD2DRD4 | |
| SCHEMBL28918260 | 0.72 | USP30 (0.53) | USP30 | |
| SCHEMBL15074625 | 0.70 | MKNK1 (0.64) | USP30DRD2DRD4DRD3 | |
| SCHEMBL28589534 | 0.69 | USP30 (0.60) | USP30 | |
| SCHEMBL28596971 | 0.69 | USP30 (0.60) | USP30 | |
| SCHEMBL29562461 | 0.68 | USP30 (0.64) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433246-B1 | 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS | MISSION THERAPEUTICS LTD (GB) | 2022-05-04 | — | — | EP | disclosed |