SCHEMBL29563296

SCHEMBL29563296

Nc1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.64
CCR5 P51681 3/20 0.64
CCR8 P51685 3/20 0.64
KDM4E B2RXH2 10/20 0.64
TP53 P04637 6/20 0.64
SMN1; SMN2 Q16637 6/20 0.64
L3MBTL1 Q9Y468 5/20 0.64
LMNA P02545 4/20 0.64
ALOX15 P16050 3/20 0.64
HTT P42858 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
ALPL P05186 1/20 0.64
HSP90AA1 P07900 1/20 0.64
ALPI P09923 1/20 0.64
ALPG P10696 1/20 0.64
MAPK1 P28482 1/20 0.64
POLB P06746 2/20 0.61
CYP1A2 P05177 1/20 0.61
METAP1 P53582 1/20 0.61
BLM P54132 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL198150 1.00 CCR1 (0.64) CCR1CCR5CCR8KDM4ETP53
SCHEMBL19053844 0.91 ASIC3 (0.60) CCR1CCR5CCR8KDM4ETP53
SCHEMBL901815 0.90 KDM4E (0.54) CCR1CCR5CCR8KDM4ETP53
SCHEMBL5685444 0.84 KDM4E (0.67) CCR1CCR5CCR8KDM4ETP53
SCHEMBL4343473 0.83 CCR1 (0.55) CCR1CCR5CCR8KDM4ETP53
SCHEMBL30732403 0.83 CCR1 (0.55) CCR1CCR5CCR8KDM4ETP53
SCHEMBL30253423 0.83 ASIC3 (0.64) CCR1CCR5CCR8KDM4ETP53
SCHEMBL12436463 0.83 KDM4E (0.64) CCR1CCR5CCR8KDM4ETP53
SCHEMBL247730 0.83 ASIC3 (0.64) CCR1CCR5CCR8KDM4ETP53
SCHEMBL4951059 0.82 KDM4E (0.70) CCR1CCR5CCR8KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119145072-A High-air-permeability fabric and preparation method thereof 南通市嘉宇斯纺织集团有限公司 2024-12-17 CN claimed
CN-114277026-B Magnetic bead for nucleic acid extraction, preparation method thereof and kit for nucleic acid extraction by magnetic bead method 深圳市易瑞生物技术股份有限公司 2023-07-14 CN claimed
CN-114277026-A Magnetic bead for nucleic acid extraction, preparation method thereof and kit for magnetic bead method nucleic acid extraction 深圳市易瑞生物技术股份有限公司 2022-04-05 CN claimed
CN-114277026-A Magnetic bead for nucleic acid extraction, preparation method thereof and kit for magnetic bead method nucleic acid extraction 深圳市易瑞生物技术股份有限公司 2022-04-05 CN disclosed