SCHEMBL198150

SCHEMBL198150

Nc1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.64
CCR5 P51681 3/20 0.64
CCR8 P51685 3/20 0.64
KDM4E B2RXH2 10/20 0.64
TP53 P04637 6/20 0.64
SMN1; SMN2 Q16637 6/20 0.64
L3MBTL1 Q9Y468 5/20 0.64
LMNA P02545 4/20 0.64
ALOX15 P16050 3/20 0.64
HTT P42858 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
ALPL P05186 1/20 0.64
HSP90AA1 P07900 1/20 0.64
ALPI P09923 1/20 0.64
ALPG P10696 1/20 0.64
MAPK1 P28482 1/20 0.64
POLB P06746 2/20 0.61
CYP1A2 P05177 1/20 0.61
METAP1 P53582 1/20 0.61
BLM P54132 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29563296 1.00 CCR1 (0.64) CCR1CCR5CCR8KDM4ETP53
SCHEMBL19053844 0.91 ASIC3 (0.60) CCR1CCR5CCR8KDM4ETP53
SCHEMBL901815 0.90 KDM4E (0.54) CCR1CCR5CCR8KDM4ETP53
SCHEMBL5685444 0.84 KDM4E (0.67) CCR1CCR5CCR8KDM4ETP53
SCHEMBL4343473 0.83 CCR1 (0.55) CCR1CCR5CCR8KDM4ETP53
SCHEMBL30732403 0.83 CCR1 (0.55) CCR1CCR5CCR8KDM4ETP53
SCHEMBL30253423 0.83 ASIC3 (0.64) CCR1CCR5CCR8KDM4ETP53
SCHEMBL12436463 0.83 KDM4E (0.64) CCR1CCR5CCR8KDM4ETP53
SCHEMBL247730 0.83 ASIC3 (0.64) CCR1CCR5CCR8KDM4ETP53
SCHEMBL4951059 0.82 KDM4E (0.70) CCR1CCR5CCR8KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114277026-B Magnetic bead for nucleic acid extraction, preparation method thereof and kit for nucleic acid extraction by magnetic bead method 深圳市易瑞生物技术股份有限公司 2023-07-14 CN claimed
EP-1810977-A2 Metal chelate complexes immobilized on solid supports for peptide preparation AplaGen GmbH (DE) 2007-07-25 EP claimed
EP-1626982-B1 METAL CHELATE COMPLEXES IMMOBILIZED ON SOLID SUPPORTS FOR PEPTIDE PREPARATION APLAGEN GMBH (DE) 2007-05-02 EP claimed
US-20070027303-A1 Metal chelate complexes immobilized on solid supports for peptide preparation APLAGEN GMBH (DE) 2007-02-01 US claimed
EP-1626982-A2 METAL CHELATE COMPLEXES IMMOBILIZED ON SOLID SUPPORTS FOR PEPTIDE PREPARATION AplaGen GmbH (DE) 2006-02-22 EP claimed
WO-2004104023-A2 METAL CHELATE COMPLEXES IMMOBILIZED ON SOLID SUPPORTS FOR PEPTIDE PREPARATION APLAGEN GMBH (DE) 2004-12-02 WO claimed
WO-2023071855-A1 HYDRAZONE-BASED ZN (II) COORDINATION COMPLEX PHOTOCHROMIC MATERIAL, PREPARATION AND USE THEREOF 南京邮电大学 2023-05-04 WO disclosed
WO-2021105086-A1 NON-THIOL NITROGEN BASED HYDROPHOBIC POLYMER BRUSH MATERIALS AND USE THEREOF FOR MODIFICATION OF SUBSTRATE SURFACES MERCK PATENT GMBH (DE) 2021-06-03 WO disclosed
US-10934293-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-02 US disclosed
US-10680183-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-09 US disclosed
WO-2019072143-A1 4-AMINOPYRIDINE DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF 上海迪诺医药科技有限公司 2019-04-18 WO disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
WO-2000020626-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE, INC. (US) 2000-04-13 WO disclosed
US-6013802-A AS FLUROESCENT INDICATORS FOR DETECTION AND QUANTIFICATION OF METAL IONS MOLECULAR PROBES, INC. (US) 2000-01-11 US disclosed
EP-0885233-A1 TERPYRIDINE-PLATINUM(II) COMPLEXES ISIS INNOVATION LIMITED (GB) 1998-12-23 EP disclosed
WO-1997027202-A1 TERPYRIDINE-PLATINUM(II) COMPLEXES ISIS INNOVATION LIMITED (GB) 1997-07-31 WO disclosed
US-5648270-A FLUORESCENT INDICATORS USING METAL-PYRIDINE COMPLEXES MOLECULAR PROBES, INC. (US) 1997-07-15 US disclosed
US-5104988-A Colorfast metallized dyes FUJI PHOTO FILM CO., LTD. (JP) 1992-04-14 US disclosed
US-4960895-A AS A LIGAND FOR MAKING METALLIZED DYES FUJI PHOTO FILM CO., LTD. (JP) 1990-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027303-A1 Metal chelate complexes immobilized on solid supports for peptide preparation SPR, RPS27A, CDC37 CCR1 2196/4885CCR5 3402/4885CCR8 1729/4885
US-10934293-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OPA1 CCR1 4287/4885CCR5 1985/4885CCR8 2663/4885
US-10680183-B2 Organic electroluminescent materials and devices PNMT, CYCS, NES CCR1 3974/4885CCR5 2377/4885CCR8 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.