SCHEMBL29564004

SCHEMBL29564004

Nc1cncc(Oc2cccc(Oc3cncc(N)c3)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
ALDH1A1 P00352 6/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MAPT P10636 2/20 0.55
MITF O75030 1/20 0.55
GAA P10253 1/20 0.55
GFER P55789 1/20 0.55
NLRP1 Q9C000 1/20 0.55
NOD2 Q9HC29 1/20 0.55
MAOB P27338 1/20 0.53
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
NLRP3 Q96P20 1/20 0.44
KDM4E B2RXH2 1/20 0.44
BRCA1 P38398 1/20 0.44
HBB P68871 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564492 0.89 KCNH2 (0.43) LMNATDP1ALDH1A1MEN1KMT2A
SCHEMBL2442117 0.88 MAOB (0.59) LMNATDP1ALDH1A1MEN1KMT2A
SCHEMBL29564344 0.85 SCN9A (0.53) TDP1ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL6931798 0.85 LMNA (0.63) LMNATDP1ALDH1A1SMN1; SMN2
SCHEMBL20554364 0.84 TSHR (0.47) LMNAALDH1A1MAPTMAOBHSD17B10
SCHEMBL30132565 0.84 TSHR (0.47) LMNAALDH1A1MAPTMAOBHSD17B10
SCHEMBL2084506 0.80 MAOB (0.55) LMNATDP1ALDH1A1MEN1KMT2A
SCHEMBL6928997 0.79 ALDH1A1 (0.41) LMNATDP1ALDH1A1MEN1KMT2A
SCHEMBL6289536 0.78 MAOB (0.82) LMNATDP1ALDH1A1MEN1KMT2A
SCHEMBL6289774 0.78 MAOB (0.82) LMNATDP1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113968971-B Preparation method of soluble and low-temperature rapid imidization polyimide film 富优特(山东)新材料科技有限公司 2022-05-27 CN claimed