Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.42 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694973 | 0.85 | ACE (0.44) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL29150853 | 0.84 | ACE (0.43) | ACEGYS1P2RX7KMT2AMEN1 | |
| SCHEMBL6705720 | 0.84 | ACE (0.43) | ACEGYS1P2RX7KMT2AMEN1 | |
| SCHEMBL31694803 | 0.79 | ACE (0.43) | ACEP2RX7KMT2AMEN1POLB | |
| SCHEMBL2583834 | 0.79 | P2RX7 (0.48) | ACEGYS1P2RX7KMT2AMEN1 | |
| SCHEMBL2583832 | 0.79 | P2RX7 (0.48) | ACEGYS1P2RX7KMT2AMEN1 | |
| SCHEMBL10881007 | 0.78 | TP53 (0.44) | ACEGYS1P2RX7KMT2AMEN1 | |
| SCHEMBL10881010 | 0.78 | TP53 (0.44) | ACEGYS1P2RX7KMT2AMEN1 | |
| SCHEMBL31694874 | 0.78 | ACE (0.42) | ACEGYS1P2RX7KMT2AMEN1 | |
| SCHEMBL1914212 | 0.78 | P2RX7 (0.51) | ACEP2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073502-A1 | USE OF BIOMARKER IN PREPARATION OF LUNG CANCER DETECTION REAGENT AND RELATED METHOD | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2022-04-14 | — | — | WO | claimed |
| WO-2022073502-A1 | USE OF BIOMARKER IN PREPARATION OF LUNG CANCER DETECTION REAGENT AND RELATED METHOD | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2022-04-14 | — | — | WO | disclosed |