Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144264 | 0.72 | KDM4E (0.49) | POLBKDM4EPARP1PARP2HDAC6 | |
| SCHEMBL22345501 | 0.65 | POLB (0.37) | POLBKDM4ERAB9A | |
| SCHEMBL22345500 | 0.64 | KDM4E (0.38) | POLBKDM4ERAB9A | |
| SCHEMBL22345504 | 0.62 | NSD2 (0.36) | POLBKDM4ERAB9A | |
| SCHEMBL22144129 | 0.61 | POLB (0.33) | POLB | |
| SCHEMBL28634474 | 0.57 | HDAC6 (0.46) | POLBPARP1PARP2HDAC6 | |
| Hydrochloric Acid SCHEMBL22345579 | 0.56 | HDAC6 (0.45) | POLBPARP1PARP2HDAC6 | |
| SCHEMBL9095253 | 0.56 | KDM4E (0.58) | POLBKDM4EPARP1PARP2HDAC6 | |
| SCHEMBL22144102 | 0.55 | PRNP (0.42) | KDM4EHDAC6 | |
| SCHEMBL6467222 | 0.54 | KMO (0.40) | POLBKDM4EHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220132847-A1 | CINNOLINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220132847-A1 | CINNOLINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | NOTUM, DDT, CYP51A1 | POLB 721/4885KDM4E 3584/4885RAB9A 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.