Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564174 | 0.72 | POLB (0.33) | KDM4EPOLBHDAC6PARP1PARP2 | |
| SCHEMBL28634474 | 0.69 | HDAC6 (0.46) | POLBTSHRRXFP1PRNPMAPK10 | |
| Hydrochloric Acid SCHEMBL22345579 | 0.68 | HDAC6 (0.45) | POLBTSHRRXFP1PRNPMAPK10 | |
| SCHEMBL15079141 | 0.67 | TSHR (0.56) | KDM4EPOLBTSHRRXFP1PRNP | |
| SCHEMBL6535305 | 0.67 | KDM4E (0.52) | KDM4EPOLBTSHRRXFP1PRNP | |
| SCHEMBL8022993 | 0.67 | KDM4E (0.97) | KDM4EPOLBTSHRRXFP1PRNP | |
| Bromide SCHEMBL15056150 | 0.66 | POLB (0.57) | KDM4EPOLBTSHRRXFP1PRNP | |
| Bromide SCHEMBL8512189 | 0.66 | KDM4E (1.00) | KDM4EPOLBTSHRCYP2D6HSD17B10 | |
| Iodide SCHEMBL29210094 | 0.66 | KDM4E (0.94) | KDM4EPOLBTSHRRXFP1PRNP | |
| SCHEMBL22345504 | 0.66 | NSD2 (0.36) | KDM4EPOLBRXFP1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127168-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | disclosed |