SCHEMBL29564428

SCHEMBL29564428

C=Cc1ccc2c(c1)C(CCCCCC)(CCCCCC)c1cc(C=C)ccc1-2

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.33
MMP9 P14780 4/20 0.33
MMP8 P22894 4/20 0.33
MMP13 P45452 4/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CNR1 P21554 3/20 0.32
CNR2 P34972 3/20 0.32
CPT1A P50416 1/20 0.32
PDK2 Q15119 1/20 0.31
ALDH1A1 P00352 1/20 0.30
APP P05067 1/20 0.30
TP53 P04637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3786364 1.00 MMP2 (0.33) MMP2MMP9MMP8MMP13CA1
SCHEMBL28036056 1.00 MMP2 (0.33) MMP2MMP9MMP8MMP13CA1
SCHEMBL3555353 0.93 PDK2 (0.38) MMP2MMP9MMP8MMP13CA1
SCHEMBL28641127 0.93 PDK2 (0.38) MMP2MMP9MMP8MMP13CA1
SCHEMBL3553115 0.93 PDK2 (0.38) MMP2MMP9MMP8MMP13CA1
SCHEMBL28643159 0.93 PDK2 (0.38) MMP2MMP9MMP8MMP13CA1
SCHEMBL28656779 0.92 ATM (0.32)
SCHEMBL28643231 0.92 ATM (0.32)
SCHEMBL16541590 0.91 DNM1 (0.39)
Naphthalene SCHEMBL28000573 0.89 PDK2 (0.36) MMP2MMP9MMP8MMP13CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022073065-A1 TRIPLET QUENCHER THE UNIVERSITY OF QUEENSLAND (AU) 2022-04-14 WO disclosed