Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 11/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564436 | 1.00 | THRA (0.43) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497293 | 0.80 | THRA (0.52) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL24329142 | 0.80 | SLC5A1 (0.54) | — | |
| SCHEMBL10498806 | 0.78 | THRA (0.51) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL24329120 | 0.78 | MAPT (0.47) | CYP1A2MEN1KMT2A | |
| SCHEMBL29564507 | 0.78 | MAPT (0.60) | CYP1A2RECQLKMT2A | |
| SCHEMBL25207853 | 0.77 | KAT8 (0.57) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497557 | 0.77 | KAT8 (0.57) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498129 | 0.76 | THRA (0.51) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498022 | 0.74 | KCNK2 (0.51) | THRATHRBATG4BPLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022080346-A1 | NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF | 国立大学法人佐賀大学 | 2022-04-21 | — | — | WO | disclosed |