SCHEMBL29564504

SCHEMBL29564504

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 4/20 0.56
▸ IL23R Q5VWK5 11/20 0.55
▸ PRMT1 Q99873 1/20 0.55
▸ UTS2R Q9UKP6 1/20 0.54
▸ KISS1R Q969F8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564832 1.00 GHSR (0.56) GHSRIL23RPRMT1UTS2RKISS1R
SCHEMBL29938218 0.98 GHSR (0.58) GHSRIL23RPRMT1UTS2RKISS1R
SCHEMBL29937863 0.97 GHSR (0.59) GHSRIL23RUTS2RKISS1R
SCHEMBL29938488 0.97 GHSR (0.59) GHSRIL23RUTS2RKISS1R
SCHEMBL11420763 0.96 IL23R (0.59) GHSRIL23RPRMT1UTS2RKISS1R
SCHEMBL11420715 0.96 IL23R (0.59) GHSRIL23RPRMT1UTS2RKISS1R
SCHEMBL29522651 0.94 GHSR (0.60) GHSRIL23RUTS2RKISS1R
SCHEMBL31514545 0.94 GHSR (0.59) GHSRIL23RUTS2RKISS1R
SCHEMBL30602952 0.94 GHSR (0.59) GHSRIL23RUTS2RKISS1R
SCHEMBL30502635 0.94 UTS2R (0.63) GHSRIL23RPRMT1UTS2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases BCN PEPTIDES, S.A. (ES) 2025-05-13 — — US claimed
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases BCN PEPTIDES, S.A. (ES) 2025-05-13 — — US disclosed
EP-4297727-A1 METHODS AND THERAPEUTIC COMBINATIONS FOR TREATING IDIOPATHIC INTRACRANIAL HYPERTENSION AND CLUSTER HEADACHES NBO Pharma LLC (US) 2024-01-03 — — EP disclosed
EP-4281041-A1 INTRANASAL FORMULATIONS AND DELIVERY OF SOMATOSTATIN MIMETICS AND USES THEREOF NBO Pharma LLC (US) 2023-11-29 — — EP disclosed
WO-2022182779-A9 METHODS AND THERAPEUTIC COMBINATIONS FOR TREATING IDIOPATHIC INTRACRANIAL HYPERTENSION AND CLUSTER HEADACHES NBO PHARMA LLC (US) 2023-06-29 — — WO disclosed
WO-2022182779-A1 METHODS AND THERAPEUTIC COMBINATIONS FOR TREATING IDIOPATHIC INTRACRANIAL HYPERTENSION AND CLUSTER HEADACHES NBO PHARMA LLC (US) 2022-09-01 — — WO disclosed
WO-2022159593-A1 INTRANASAL FORMULATIONS AND DELIVERY OF SOMATOSTATIN MIMETICS AND USES THEREOF NBO PHARMA LLC (US) 2022-07-28 — — WO disclosed
US-20220135640-A1 CORTISTATIN OR AN ANALOGUE THEREOF AS A PHARMACEUTICALLY ACTIVE AGENT IN LATENT FORM CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2022-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases GHSR, GIPR, GHRHR GHSR 1/4885IL23R 158/4885PRMT1 2020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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