SCHEMBL29565161 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	QPCT	Q16769	1/20	0.38

▸	QPCTL	Q9NXS2	1/20	0.38

▸	L3MBTL1	Q9Y468	1/20	0.35

▸	MDM2	Q00987	16/20	0.35

▸	TP53	P04637	10/20	0.35

▸	CYP1A2	P05177	1/20	0.35

▸	METAP2	P50579	1/20	0.35

▸	NPC1	O15118	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	LMNA	P02545	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	OPRK1	P41145	1/20	0.33

▸	HTT	P42858	1/20	0.33

▸	RAB9A	P51151	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24394591	1.00	QPCT (0.38)	QPCTQPCTLL3MBTL1MDM2TP53
SCHEMBL29565225	0.81	QPCT (0.40)	QPCTQPCTLMDM2TP53CYP1A2
SCHEMBL22869317	0.81	QPCT (0.40)	QPCTQPCTLMDM2TP53CYP1A2
SCHEMBL25840630	0.81	QPCT (0.34)	QPCTQPCTLMDM2TP53CYP1A2
SCHEMBL29565730	0.79	PLAU (0.38)	QPCTQPCTLL3MBTL1MDM2TP53
SCHEMBL24394615	0.79	PLAU (0.38)	QPCTQPCTLL3MBTL1MDM2TP53
SCHEMBL24394484	0.77	HSD11B1 (0.33)	QPCTQPCTLMDM2TP53CYP1A2
SCHEMBL29564739	0.77	HSD11B1 (0.33)	QPCTQPCTLMDM2TP53CYP1A2
SCHEMBL24300631	0.77	MDM2 (0.41)	MDM2TP53
SCHEMBL28728598	0.76	NT5E (0.36)	QPCTQPCTLMDM2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022090711-A1	COMPOUNDS AS CD73 INHIBITORS	AdoRx Therapeutics Limited (GB)	2022-05-05	—	—	WO	disclosed