Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537363 | 0.92 | L3MBTL1 (0.46) | DAOPOLBSMN1; SMN2LMNARXFP1 | |
| SCHEMBL5536615 | 0.84 | KMT2A (0.47) | POLBSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5535242 | 0.82 | SMN1; SMN2 (0.46) | POLBSMN1; SMN2LMNARXFP1EGFR | |
| SCHEMBL5537750 | 0.82 | SMN1; SMN2 (0.46) | POLBSMN1; SMN2LMNARXFP1EGFR | |
| SCHEMBL21990269 | 0.80 | POLB (0.46) | POLBSMN1; SMN2LMNAEGFRMEN1 | |
| SCHEMBL22044890 | 0.78 | LMNA (0.42) | POLBSMN1; SMN2LMNARXFP1EGFR | |
| SCHEMBL29668460 | 0.72 | KMT2A (0.66) | DAOPOLBTSHRHSD17B10MEN1 | |
| SCHEMBL28274692 | 0.72 | TSHR (0.50) | POLBSMN1; SMN2LMNATSHRCYP2C9 | |
| SCHEMBL5537048 | 0.70 | LMNA (0.44) | POLBSMN1; SMN2LMNARXFP1EGFR | |
| SCHEMBL21802604 | 0.69 | MAP2K1 (0.45) | POLBSMN1; SMN2LMNAEGFRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869369-B | Five-membered and six-membered nitrogen heteroaromatic ring compound, preparation method thereof, medicinal composition and application thereof | 厦门大学 | 2022-06-28 | — | — | CN | disclosed |
| US-11292787-B2 | Five-membered-fused-six-membered aza-aromatic ring compound, preparation method thereof, pharmaceutical composition and application thereof | XIAMEN UNIVERSITY (CN) | 2022-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292787-B2 | Five-membered-fused-six-membered aza-aromatic ring compound, preparation method thereof, pharmaceutical composition and application thereof | KRAS, NRAS, RASSF5 | DAO 1911/4885POLB 3970/4885SMN1; SMN2 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.