Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22905505 | 0.81 | CA2 (0.39) | CA2GAA | |
| SCHEMBL19656903 | 0.73 | UGT2B17 (0.30) | — | |
| SCHEMBL29615910 | 0.69 | CA2 (0.39) | CA2GAAMAPTHTT | |
| SCHEMBL22905481 | 0.66 | POLB (0.37) | CA2MAPTSMN1; SMN2 | |
| SCHEMBL22905483 | 0.65 | CA2 (0.33) | CA2 | |
| SCHEMBL22905676 | 0.65 | CA2 (0.34) | CA2 | |
| SCHEMBL22905581 | 0.61 | POLB (0.60) | CA2SMN1; SMN2 | |
| SCHEMBL22905580 | 0.61 | CDC7 (0.40) | CA2MAPTHTT | |
| SCHEMBL29567705 | 0.61 | POLB (0.60) | CA2SMN1; SMN2 | |
| SCHEMBL13845052 | 0.60 | CYP19A1 (0.42) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555571-A | N- ((1,2,3,5,6, 7-hexahydro-s-indacen-4-yl) carbamoyl) -4,5,6, 7-tetrahydrobenzofuran-2-sulfonamide derivatives and related compounds as NLPR3 modulators for the treatment of Multiple Sclerosis (MS) | 祖玛珍生物科学有限公司 | 2022-05-27 | — | — | CN | disclosed |