Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22736527 | 0.88 | RPS6KB1 (0.33) | RPS6KB1 | |
| SCHEMBL29567159 | 0.88 | RPS6KB1 (0.33) | RPS6KB1 | |
| SCHEMBL29567573 | 0.79 | JAK2 (0.34) | — | |
| SCHEMBL22716894 | 0.79 | JAK2 (0.34) | — | |
| SCHEMBL29480651 | 0.76 | — | — | |
| SCHEMBL22736528 | 0.76 | RPS6KB1 (0.34) | RPS6KB1 | |
| SCHEMBL22735769 | 0.76 | EGLN1 (0.33) | — | |
| SCHEMBL22736319 | 0.76 | — | — | |
| SCHEMBL22735954 | 0.76 | EGLN1 (0.34) | — | |
| SCHEMBL29480690 | 0.76 | OGA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976612-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD (IN) | 2022-04-06 | — | — | EP | disclosed |