⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18381559 | 0.84 | — | — | |
| SCHEMBL11730139 | 0.84 | — | — | |
| SCHEMBL5888224 | 0.81 | FDPS (0.37) | — | |
| SCHEMBL15896625 | 0.81 | SRC (0.34) | — | |
| SCHEMBL9900674 | 0.79 | POLB (0.37) | — | |
| SCHEMBL11665182 | 0.79 | SLC5A2 (0.36) | — | |
| SCHEMBL15896554 | 0.79 | TRPA1 (0.33) | — | |
| SCHEMBL10958808 | 0.79 | CYP2A6 (0.33) | — | |
| SCHEMBL9899893 | 0.79 | MEN1 (0.38) | — | |
| SCHEMBL10959953 | 0.79 | CYP2A6 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399878-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2008-07-15 | — | — | US | claimed |
| US-20070197499-A1 | Pharmaceutical compounds | NICOX S.A. | 2007-08-23 | — | — | US | claimed |
| US-7186753-B1 | Pharmaceutical compounds | NICOX S.A. (FR) | 2007-03-06 | — | — | US | claimed |
| US-20040023890-A1 | Drugs for diabetes | NICOX S.A. (FR) | 2004-02-05 | — | — | US | claimed |
| CN-1433396-A | Pharmaceutical compounds | NICOX SA (FR) | 2003-07-30 | — | — | CN | claimed |
| EP-1324974-A2 | DRUGS FOR DIABETES | Nicox S.A. (FR) | 2003-07-09 | — | — | EP | claimed |
| WO-2002030867-A2 | DRUGS FOR DIABETES | NICOX S.A. (FR) | 2002-04-18 | — | — | WO | claimed |
| US-7759392-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2010-07-20 | — | — | US | disclosed |
| US-20090170941-A1 | Pharmaceutical Compounds | NICOX S.A. (FR) | 2009-07-02 | — | — | US | disclosed |
| US-7399878-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2008-07-15 | — | — | US | disclosed |
| US-7378437-B2 | Use for the diabetes treatment of compounds or salts thereof, having the following general formula (I): A-(B)b0-(C)c0-NO2 wherein A contains the radical of a drug having an antiiflammatory or analgesic activity, B is a bivalen: linking | NICOX S.A. (FR) | 2008-05-27 | — | — | US | disclosed |
| US-20070197499-A1 | Pharmaceutical compounds | NICOX S.A. | 2007-08-23 | — | — | US | disclosed |
| CN-1923797-A | Pharmaceutical compounds | NICOX SA (FR) | 2007-03-07 | — | — | CN | disclosed |
| US-7186753-B1 | Pharmaceutical compounds | NICOX S.A. (FR) | 2007-03-06 | — | — | US | disclosed |
| CN-1289466-C | Pharmaceutical compounds | NICOX SA (FR) | 2006-12-13 | — | — | CN | disclosed |
| EP-1593664-A1 | Nitric esters derivatives of ferulic acid and sulindac with pharmaceutical activity | Nicox S.A (FR) | 2005-11-09 | — | — | EP | disclosed |
| US-20040023890-A1 | Drugs for diabetes | NICOX S.A. (FR) | 2004-02-05 | — | — | US | disclosed |
| CN-1433396-A | Pharmaceutical compounds | NICOX SA (FR) | 2003-07-30 | — | — | CN | disclosed |
| EP-1324974-A2 | DRUGS FOR DIABETES | Nicox S.A. (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030867-A2 | DRUGS FOR DIABETES | NICOX S.A. (FR) | 2002-04-18 | — | — | WO | disclosed |