SCHEMBL2956869

SCHEMBL2956869

C(=C/c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1)\c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.55
▸ KDM4E B2RXH2 1/20 0.55
▸ ATM Q13315 1/20 0.55
▸ HDAC4 P56524 1/20 0.41
▸ TSPO P30536 1/20 0.39
▸ CHEK1 O14757 3/20 0.38
▸ AKR1C4 P17516 1/20 0.38
▸ AKR1C3 P42330 1/20 0.38
▸ AKR1C2 P52895 1/20 0.38
▸ AKR1C1 Q04828 1/20 0.38
▸ PTGER4 P35408 1/20 0.37
▸ KMT2A Q03164 5/20 0.36
▸ IL1R1 P14778 1/20 0.36
▸ MEN1 O00255 4/20 0.36
▸ MAPT P10636 2/20 0.36
▸ GAA P10253 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ POLB P06746 2/20 0.35
▸ RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2956875 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL2956174 0.98 L3MBTL1 (0.56) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL2956171 0.98 L3MBTL1 (0.56) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL13237957 0.97 L3MBTL1 (0.55) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL13237967 0.93 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL2446031 0.92 KDM4E (0.56) L3MBTL1KDM4EATMHDAC4AKR1C4
SCHEMBL13444158 0.92 KDM4E (0.49) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL13237923 0.91 L3MBTL1 (0.51) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL17879400 0.91 L3MBTL1 (0.55) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL13238013 0.90 AKR1C4 (0.48) L3MBTL1KDM4EATMHDAC4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758972-B2 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-07-20 — — US disclosed
US-7758972-B2 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-07-20 — — US disclosed
US-7758972-B2 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-07-20 — — US disclosed
US-20100066241-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-18 — — US disclosed
US-20100066241-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-18 — — US disclosed
US-20080145700-A1 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-06-19 — — US disclosed
US-20080145700-A1 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-06-19 — — US disclosed
US-20080145700-A1 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-06-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100066241-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same IL33, ORMDL3, CCND3 L3MBTL1 482/4885KDM4E 4343/4885ATM 4786/4885
US-20080145700-A1 Carbazole substituents; light emitting layer between a pair of electrodes, blue light emission with excellent color purity CYP1B1, CYBA, CYP4B1 L3MBTL1 1373/4885KDM4E 2169/4885ATM 2957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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