Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 9/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.68 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.64 |
| ▸ | TTR | P02766 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | PGR | P06401 | 2/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | EYA2 | O00167 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Poztinurad SCHEMBL15698085 | 1.00 | EYA3 (1.00) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| SCHEMBL15698033 | 0.91 | EYA3 (0.83) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| SCHEMBL25814802 | 0.90 | EYA3 (0.81) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| SCHEMBL25892406 | 0.90 | EYA3 (0.81) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| SCHEMBL20702031 | 0.89 | EYA3 (0.80) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| SCHEMBL22680472 | 0.87 | EYA3 (0.77) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| SCHEMBL25815018 | 0.87 | EYA3 (0.77) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| SCHEMBL20702027 | 0.84 | EYA3 (0.72) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| Pozdeutinurad SCHEMBL22032803 | 0.81 | EYA3 (0.68) | EYA3CYP2C19SLC22A12TTRCYP2C9 | |
| Pozdeutinurad SCHEMBL30421663 | 0.80 | EYA3 (0.67) | EYA3CYP2C19SLC22A12TTRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957629-B1 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | ARTHROSI THERAPEUTICS INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3957629-C0 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | ARTHROSI THERAPEUTICS INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3957629-A1 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | Arthrosi Therapeutics, Inc. (US) | 2022-02-23 | — | — | EP | disclosed |