Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 8/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | TTR | P02766 | 3/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EYA2 | O00167 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Poztinurad SCHEMBL29569243 | 0.90 | EYA3 (1.00) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| Poztinurad SCHEMBL15698085 | 0.90 | EYA3 (1.00) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| SCHEMBL25814848 | 0.86 | EYA3 (0.62) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| SCHEMBL15698033 | 0.81 | EYA3 (0.83) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| SCHEMBL25892406 | 0.80 | EYA3 (0.81) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| SCHEMBL20702031 | 0.79 | EYA3 (0.80) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| SCHEMBL18058593 | 0.78 | CYP2C19 (0.81) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| SCHEMBL25815018 | 0.77 | EYA3 (0.77) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| SCHEMBL22680472 | 0.77 | EYA3 (0.77) | EYA3CYP2C19CYP2C9TTRNR1H4 | |
| SCHEMBL25814830 | 0.76 | TTR (0.64) | EYA3CYP2C19CYP2C9TTRNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218563-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ARTHROSI THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218563-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ATP6V1B1, REN, CYP27B1 | EYA3 3141/4885CYP2C19 826/4885CYP2C9 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.