Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.39 |
| ▸ | RAMP3 | O60896 | 7/20 | 0.39 |
| ▸ | CALCR | P30988 | 7/20 | 0.39 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.38 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.38 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.37 |
| ▸ | TFPI | P10646 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440026 | 0.92 | MAPK8 (0.46) | KEAP1MAPK8MAPK9MAPK10RAMP3 | |
| SCHEMBL29824839 | 0.91 | MEN1 (0.40) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL31195953 | 0.91 | MAPK8 (0.49) | KEAP1MAPK8MAPK9MAPK10RAMP3 | |
| SCHEMBL8720817 | 0.89 | MAPK8 (0.44) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL8720811 | 0.89 | MAPK8 (0.44) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL29993959 | 0.89 | MAPK8 (0.52) | KEAP1MAPK8MAPK9MAPK10REN | |
| SCHEMBL30961943 | 0.89 | KDM1A (0.50) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL29825310 | 0.88 | MAPK8 (0.44) | KEAP1MAPK8MAPK9MAPK10 | |
| SCHEMBL29886731 | 0.88 | MAPK8 (0.41) | KEAP1MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL30171144 | 0.88 | KDM1A (0.48) | KEAP1MAPK8MAPK9MAPK10KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118697898-A | Targeting synergistic drug system based on macrophage exosome and preparation method thereof | 首都医科大学附属北京朝阳医院 | 2024-09-27 | — | — | CN | disclosed |
| CN-115120552-A | Polypeptide drug-loaded microneedle patch capable of releasing drug in microenvironment response manner, preparation and application | 华中科技大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-114099664-B | Treg cell exosome-based targeted synergistic drug system and preparation method thereof | 首都医科大学附属北京朝阳医院 | 2022-09-27 | — | — | CN | disclosed |
| EP-3320923-B1 | FLUORESCENT IMAGING AGENTS | VISEN MEDICAL INC (US) | 2022-04-06 | — | — | EP | disclosed |