Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 11/20 | 0.43 |
| ▸ | NPY1R | P25929 | 8/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.43 |
| ▸ | NPY2R | P49146 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720817 | 1.00 | MAPK8 (0.44) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL30974427 | 0.96 | KDM1A (0.43) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL29687469 | 0.96 | MAPK8 (0.48) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL29437943 | 0.96 | MAPK8 (0.43) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL29496543 | 0.92 | MEN1 (0.44) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL29825310 | 0.92 | MAPK8 (0.44) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL29663559 | 0.92 | MAPK8 (0.46) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL31097677 | 0.92 | KDM1A (0.47) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL31097702 | 0.92 | KDM1A (0.47) | MAPK8MAPK9MAPK10NPY4RNPY1R | |
| SCHEMBL31239106 | 0.92 | KDM1A (0.47) | MAPK8MAPK9MAPK10NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570244-B1 | Process for preparing peptides having a C-terminal proline amide | SANKYO CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0570244-A1 | Process for preparing peptides having a c-terminal proline amide | SANKYO COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |