SCHEMBL8720817

SCHEMBL8720817

CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 1/20 0.44
▸ MAPK9 P45984 1/20 0.44
▸ MAPK10 P53779 1/20 0.44
▸ NPY4R P50391 11/20 0.43
▸ NPY1R P25929 8/20 0.43
▸ NPY5R Q15761 7/20 0.43
▸ NPY2R P49146 4/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ KEAP1 Q14145 1/20 0.41
▸ PRCP P42785 1/20 0.40
▸ KDM1A O60341 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8720811 1.00 MAPK8 (0.44) MAPK8MAPK9MAPK10NPY4RNPY1R
SCHEMBL30974427 0.96 KDM1A (0.43) MAPK8MAPK9MAPK10NPY4RNPY1R
SCHEMBL29687469 0.96 MAPK8 (0.48) MAPK8MAPK9MAPK10NPY4RNPY1R
SCHEMBL29437943 0.96 MAPK8 (0.43) MAPK8MAPK9MAPK10NPY4RNPY1R
SCHEMBL29496543 0.92 MEN1 (0.44) MAPK8MAPK9MAPK10MEN1KMT2A
SCHEMBL29825310 0.92 MAPK8 (0.44) MAPK8MAPK9MAPK10NPY4RNPY1R
SCHEMBL29663559 0.92 MAPK8 (0.46) MAPK8MAPK9MAPK10NPY4RNPY1R
SCHEMBL31097677 0.92 KDM1A (0.47) MAPK8MAPK9MAPK10NPY4RNPY1R
SCHEMBL31097702 0.92 KDM1A (0.47) MAPK8MAPK9MAPK10NPY4RNPY1R
SCHEMBL31239106 0.92 KDM1A (0.47) MAPK8MAPK9MAPK10NPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2026-04-02 — — US disclosed
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2025-12-18 — — US disclosed
CN-120694407-A Tripeptide-chlorogenic acid synergistic antioxidant compound and application thereof 重庆大学 2025-09-26 — — CN disclosed
EP-4608437-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 — — EP disclosed
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-07-31 — — US disclosed
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-07-29 — — US disclosed
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-04-24 — — US disclosed
US-20240269269-A1 Self-Assembling Nanoparticles VACCITECH NORTH AMERICA, INC. (US) 2024-08-15 — — US disclosed
CN-118103059-A Self-assembled nanoparticles based on amphiphilic peptides 巴林萨斯生物疗法北美公司 2024-05-28 — — CN disclosed
WO-2024092028-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER VACCITECH NORTH AMERICA, INC. (US) 2024-05-02 — — WO disclosed
EP-4294431-A1 SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES Vaccitech North America, Inc. (US) 2023-12-27 — — EP disclosed
WO-2022177993-A1 SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES VACCITECH NORTH AMERICA, INC. (US) 2022-08-25 — — WO disclosed
EP-0570244-B1 Process for preparing peptides having a C-terminal proline amide SANKYO CO (JP) 1998-02-11 — — EP disclosed
EP-0570244-A1 Process for preparing peptides having a c-terminal proline amide SANKYO COMPANY LIMITED (JP) 1993-11-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides IAPP, BRCA1, ANXA11 MAPK8 3032/4885MAPK9 2940/4885MAPK10 2072/4885
US-20240269269-A1 Self-Assembling Nanoparticles UBE2B, CD4, UBE2G2 MAPK8 2073/4885MAPK9 3209/4885MAPK10 3137/4885
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER IL2, IFNG, ICOS MAPK8 2621/4885MAPK9 3231/4885MAPK10 885/4885
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES UBE2B, CD4, HRH1 MAPK8 2094/4885MAPK9 3243/4885MAPK10 3181/4885
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES VIP, HM13, SPPL2B MAPK8 2911/4885MAPK9 2423/4885MAPK10 1588/4885
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response MYD88, ICOS, CD4 MAPK8 1612/4885MAPK9 967/4885MAPK10 1468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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