Bexlosteride

Bexlosteride

SCHEMBL29569846

CN1C(=O)CC[C@@H]2c3ccc(Cl)cc3CC[C@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 20/20 1.00
SRD5A2 P31213 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bexlosteride SCHEMBL7194610 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
Bexlosteride SCHEMBL13735634 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
Bexlosteride SCHEMBL225679 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
Bexlosteride SCHEMBL7798944 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
Bexlosteride SCHEMBL225678 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL7798977 0.89 SRD5A1 (0.80) SRD5A1SRD5A2
SCHEMBL7798978 0.89 SRD5A1 (0.80) SRD5A1SRD5A2
SCHEMBL7798956 0.84 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL7796416 0.84 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL7796411 0.84 SRD5A1 (1.00) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4447954-A1 HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS Icahn School of Medicine at Mount Sinai (US) 2024-10-23 EP disclosed
EP-4448510-A1 INHIBITORS OF MET KINASE Kinnate Biopharma Inc. (US) 2024-10-23 EP disclosed
EP-4308115-A1 HETEROAROYL AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF Merck Sharp & Dohme LLC (US) 2024-01-24 EP disclosed
WO-2023114809-A1 INHIBITORS OF MET KINASE KINNATE BIOPHARMA INC. (US) 2023-06-22 WO disclosed
WO-2023114472-A1 HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-06-22 WO disclosed
WO-2022203930-A1 FLUOROGENIC CYANINE CARBAMATES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-09-29 WO disclosed
WO-2022197577-A1 HETEROAROYL AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2022-09-22 WO disclosed
WO-2022076735-A1 INHIBITORS OF THE BROMODOMAIN PHD FINGER TRANSCRIPTION FACTOR (BPTF) AS ANTI-CANCER AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-04-14 WO disclosed