Bexlosteride

Bexlosteride

SCHEMBL225679

CN1C(=O)CCC2c3ccc(Cl)cc3CCC21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 20/20 1.00
SRD5A2 P31213 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bexlosteride SCHEMBL29569846 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
Bexlosteride SCHEMBL7194610 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
Bexlosteride SCHEMBL13735634 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
Bexlosteride SCHEMBL7798944 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
Bexlosteride SCHEMBL225678 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL7798977 0.89 SRD5A1 (0.80) SRD5A1SRD5A2
SCHEMBL7798978 0.89 SRD5A1 (0.80) SRD5A1SRD5A2
SCHEMBL7798956 0.84 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL7796416 0.84 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL7796411 0.84 SRD5A1 (1.00) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 893 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608405-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL Veradermics, Incorporated (US) 2025-09-03 EP claimed
US-20250100986-A1 BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-03-27 US claimed
US-20250032470-A1 Electrophilic Androgen Receptor (AR) Antagonists for AR Downregulation and Ferroptosis Induction in Cancer Cells WAYNE STATE UNIVERSITY (US) 2025-01-30 US claimed
US-12168803-B2 Compositions and methods for screening and diagnosis of prostate cancer DANA-FARBER CANCER INSTITUTE, INC. (US) 2024-12-17 US claimed
US-20240391883-A1 HETEROCYCLIC COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-11-28 US claimed
EP-4446301-A2 HETEROCYCLIC COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE British Columbia Cancer Agency Branch (CA) 2024-10-16 EP claimed
EP-3988541-B1 HETEROCYCLIC COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) 2024-06-26 EP claimed
WO-2024091572-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2024-05-02 WO claimed
EP-3442942-B1 BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) 2023-11-15 EP claimed
US-11739069-B2 Modulators of resistant androgen receptor MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2023-08-29 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-0591583-B1 Benzo (f) quinolinones as 5-alpha-reductase inhibitors LILLY CO ELI (US) 2001-12-19 EP claimed
EP-0532190-B1 Benzo(f)quinolinones as 5-alpha-reductase inhibitors LILLY CO ELI (US) 2000-12-27 EP claimed
US-5541190-A TREATING BENIGN PROSTATIC HYPERPLASIA, MALE PATTERN BALDNESS, PROSTATIC CANCER, ANDROGENIC ALOPECIA ELI LILLY AND COMPANY (US) 1996-07-30 US claimed
EP-0591583-A1 Benzo (f) quinolinones as 5-alpha-reductase inhibitors ELI LILLY AND COMPANY (US) 1994-04-13 EP claimed
EP-0532190-A2 Benzo f quinolinones as 5-alpha-reductase inhibitors ELI LILLY AND COMPANY (US) 1993-03-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250100986-A1 BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS AR, SHBG, NR5A1 SRD5A1 17/4885SRD5A2 29/4885
US-20240391883-A1 HETEROCYCLIC COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE AR, KLK3, GNRHR SRD5A1 10/4885SRD5A2 42/4885
US-11739069-B2 Modulators of resistant androgen receptor AR, NR5A1, ESRRA SRD5A1 29/4885SRD5A2 27/4885
US-20250032470-A1 Electrophilic Androgen Receptor (AR) Antagonists for AR Downregulation and Ferroptosis Induction in Cancer Cells AR, GSR, GPX1 SRD5A1 340/4885SRD5A2 358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.