Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20501207 | 1.00 | KMT2A (0.41) | KMT2ATARBP2GAANPSR1KDM4E | |
| SCHEMBL21798595 | 0.86 | KDM4E (0.49) | KMT2ANPSR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL20501206 | 0.86 | KMT2A (0.41) | KMT2ATARBP2GAANPSR1KDM4E | |
| SCHEMBL21798567 | 0.80 | KDM4E (0.53) | KMT2ANPSR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL19194087 | 0.77 | KDM4E (0.59) | KMT2AKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL28060100 | 0.77 | KDM4E (0.63) | KMT2AKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20501209 | 0.77 | ALDH1A1 (0.49) | KMT2ATARBP2GAAKDM4ELMNA | |
| SCHEMBL20501193 | 0.75 | CFTR (0.38) | GAAKDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1466405 | 0.74 | CA1 (0.52) | KMT2AGAANPSR1KDM4ELMNA | |
| SCHEMBL18115479 | 0.72 | USP30 (0.56) | TARBP2GAANPSR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074589-A1 | CARBOXYLIC DIARYLTHIAZEPINEAMINES AND USES THEREFOR | KURES, INC. (US) | 2022-04-14 | — | — | WO | disclosed |