Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylamine SCHEMBL30439632 | 1.00 | CYP3A4 (0.42) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| Butylamine SCHEMBL4456944 | 0.99 | CYP3A4 (0.43) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL8856126 | 0.87 | SHBG (0.52) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL2928281 | 0.87 | SHBG (0.52) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL30899191 | 0.87 | SHBG (0.52) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| Butylamine SCHEMBL1532624 | 0.87 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL11470454 | 0.86 | CYP3A4 (0.50) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| SCHEMBL51667 | 0.86 | SHBG (0.53) | CYP3A4CYP2D6HIF1ASHBGESR1 | |
| Butylamine SCHEMBL10880274 | 0.85 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL27691619 | 0.85 | ALDH1A1 (0.40) | CYP3A4CYP2D6HIF1ASHBGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170460-B1 | Derivatives of N-[2-(tetrahydro-3,5-dioxo-1H-pyrrolizin-7a(5H)-yl)ethyl]amine | WARNER-LAMBERT COMPANY (US) | 1989-05-03 | — | — | EP | claimed |
| EP-0195898-B1 | A METHOD OF INCREASING THE LIGHT FATIGUE RESISTANCE OF A PHOTOCHROMIC COMPOSITION AND PHOTOCHROMIC COMPOSITION | AMERICAN OPTICAL CORPORATION (US) | 1988-11-02 | — | — | EP | claimed |
| EP-0134633-B1 | PHOTOCHROMIC COMPOSITION | AMERICAN OPTICAL CORPORATION (US) | 1988-06-08 | — | — | EP | claimed |
| US-4699473-A | PHOTOCOLORABILITY; LENSES | AMERICAN OPTICAL CORPORATION (US) | 1987-10-13 | — | — | US | claimed |
| US-4440672-A | SPIRO(INDOLINE-2,3'-(3'H)-NAPHTN(1,2-B)(1,4) OXAZINES), ULTRAVIOLET STABILIZER | AMERICAN OPTICAL CORPORATION (US) | 1984-04-03 | — | — | US | claimed |
| CN-118201998-A | Polyester composition and elastomer coated article made therefrom | 国际人造丝公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118103449-A | Laser transparent composition and molded article made therefrom | 国际人造丝公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118019791-A | Thermoplastic polymer composition with enhanced tracking resistance and polymer articles made therefrom | 国际人造丝公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117500881-A | Polymer composition with release properties | 国际人造丝公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116981735-A | Laser-weldable polyester compositions | 国际人造丝公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116348528-A | Flame retardant hydrolysis resistant polyester compositions and connectors made therefrom | 国际人造丝公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-114341269-A | Flame retardant polymer compositions and articles made therefrom | 国际人造丝公司 | 2022-04-12 | — | — | CN | disclosed |
| US-5585042-A | REVERSIBLE CHANGE IN COLOR WHEN EXPOSURED TO ULTRAVIOLET RADIATION | TRANSITIONS OPTICAL, INC. (US) | 1996-12-17 | — | — | US | disclosed |
| US-5395567-A | For use in ophthalmic lenses; efficient reversible color change on exposure to uv rad | PPG INDUSTRIES, INC. (US) | 1995-03-07 | — | — | US | disclosed |
| US-5369158-A | And polymer | TRANSITIONS OPTICAL, INC. (US) | 1994-11-29 | — | — | US | disclosed |
| US-5238981-A | PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-4882438-A | DURABILITY; HETEROCYCLIC IMIDE COMPOUND | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0134633-B1 | PHOTOCHROMIC COMPOSITION | AMERICAN OPTICAL CORPORATION (US) | 1988-06-08 | — | — | EP | disclosed |
| US-4699473-A | PHOTOCOLORABILITY; LENSES | AMERICAN OPTICAL CORPORATION (US) | 1987-10-13 | — | — | US | disclosed |
| US-4440672-A | SPIRO(INDOLINE-2,3'-(3'H)-NAPHTN(1,2-B)(1,4) OXAZINES), ULTRAVIOLET STABILIZER | AMERICAN OPTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |