Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29570205 | 0.82 | MAPT (0.46) | MAPTSMN1; SMN2KMT2ANPSR1MEN1 | |
| SCHEMBL23377838 | 0.81 | MAPT (0.45) | MAPTSMN1; SMN2KMT2ANPSR1MEN1 | |
| SCHEMBL23377841 | 0.81 | MAPT (0.45) | MAPTSMN1; SMN2KMT2ANPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL28557076 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2KMT2ANPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL28557077 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2KMT2ANPSR1MEN1 | |
| SCHEMBL29570358 | 0.78 | KCNN4 (0.42) | MAPTSMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL29570745 | 0.75 | MAPT (0.45) | MAPTSMN1; SMN2KMT2ANPSR1MEN1 | |
| SCHEMBL9070698 | 0.73 | MAPT (0.43) | MAPTSMN1; SMN2KMT2ANPSR1MEN1 | |
| SCHEMBL6487847 | 0.72 | ALDH1A1 (0.50) | KMT2ANPSR1HPGDALDH1A1CES2 | |
| SCHEMBL12282257 | 0.71 | AOC3 (0.42) | MAPTHTTALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802181-A | Triazolopyridine compounds as kinase inhibitors | 百时美施贵宝公司 | 2023-09-22 | — | — | CN | disclosed |
| EP-4229056-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022086828-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-04-28 | — | — | WO | disclosed |