Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.46 |
| ▸ | HTR2B | P41595 | 5/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252280 | 1.00 | HTR2C (0.46) | HTR2CHTR2BKDM1AHTR2ASLC6A2 | |
| SCHEMBL1043098 | 0.91 | HTR2C (0.43) | HTR2CHTR2BKDM1AHTR2ASLC6A2 | |
| SCHEMBL29384288 | 0.91 | HTR2C (0.43) | HTR2CHTR2BKDM1AHTR2ASLC6A2 | |
| SCHEMBL11030273 | 0.90 | HTR2C (0.42) | HTR2CHTR2BKDM1AHTR2ASLC6A2 | |
| SCHEMBL3727526 | 0.83 | TSHR (0.36) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL24216729 | 0.79 | KDM1A (0.42) | HTR2CHTR2BKDM1AHTR2ASLC6A2 | |
| SCHEMBL30409857 | 0.79 | KDM1A (0.42) | HTR2CHTR2BKDM1AHTR2ASLC6A2 | |
| SCHEMBL29946544 | 0.79 | NSD2 (0.36) | HTR2CHTR2BKDM1AHTR2ASLC6A2 | |
| SCHEMBL11632118 | 0.79 | HTR2C (0.41) | HTR2CHTR2BKDM1AHTR2ASLC6A2 | |
| SCHEMBL26132936 | 0.79 | KDM1A (0.34) | HTR2CHTR2BKDM1AHTR2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116162060-B | Synthetic method of OLED intermediate 3-substituted kephaline | 江苏广域化学有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-117460698-A | Surface-modified nanoparticles | 国立大学法人京都大学 | 2024-01-26 | — | — | CN | disclosed |
| EP-4225447-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-116514816-A | Pyrimidinone pyrrole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116162060-A | Synthetic method of OLED intermediate 3-substituted kephaline | 江苏广域化学有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-113416210-B | Rigid tetranitrogen tetradentate fourth subgroup metal complex and application thereof | 山东京博石油化工有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-113185545-B | Benzylamino-containing side arm Shan Maodi quaternary metal complex and application thereof | 吉林大学 | 2022-11-29 | — | — | CN | disclosed |
| WO-2022076625-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |