Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043098 | 1.00 | HTR2C (0.43) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL11030273 | 0.98 | HTR2C (0.42) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL252280 | 0.91 | HTR2C (0.46) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL29571908 | 0.91 | HTR2C (0.46) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL3977375 | 0.77 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL11632118 | 0.76 | HTR2C (0.41) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL3666019 | 0.75 | NLRP3 (0.32) | GAA | |
| SCHEMBL13610515 | 0.75 | KDM1A (0.44) | HTR2CHTR2BKDM1ARCOR1MEN1 | |
| SCHEMBL1374931 | 0.75 | MEN1 (0.43) | HTR2CHTR2BSLC6A2HTR2ASLC6A4 | |
| SCHEMBL3083610 | 0.75 | HTR2C (0.42) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116162060-B | Synthetic method of OLED intermediate 3-substituted kephaline | 江苏广域化学有限公司 | 2024-12-03 | — | — | CN | disclosed |
| EP-4192957-A2 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-116162060-A | Synthetic method of OLED intermediate 3-substituted kephaline | 江苏广域化学有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-116113698-A | TRPML modulators | 卡斯玛治疗公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2022032073-A2 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2022-02-10 | — | — | WO | disclosed |