Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446162 | 1.00 | POLB (0.44) | POLBCYP3A4CYP2D6CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1723028 | 0.98 | POLB (0.42) | POLBCYP3A4CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL1495175 | 0.94 | LIPG (0.50) | POLBCYP3A4CYP2D6CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28282712 | 0.92 | LIPG (0.49) | POLBCYP3A4CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL7438728 | 0.88 | ALDH1A1 (0.46) | POLBALDH1A1GAAMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL4915526 | 0.86 | ALDH1A1 (0.44) | POLBALDH1A1GAAMAPTTDP1 | |
| SCHEMBL6938190 | 0.85 | F7 (0.44) | MAPTLIPG | |
| SCHEMBL14785273 | 0.83 | CYP3A4 (0.46) | POLBCYP3A4CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL28033756 | 0.83 | POLB (0.37) | POLBCYP3A4CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL1954254 | 0.82 | POLB (0.54) | POLBCYP3A4CYP2D6CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040157-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |