Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.62 |
| ▸ | HTR2B | P41595 | 12/20 | 0.57 |
| ▸ | HTR2C | P28335 | 8/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.57 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 3/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29573468 | 0.84 | HTR2B (0.47) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL29573969 | 0.83 | HRH2 (0.54) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL29574436 | 0.79 | ADORA1 (0.57) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL12805062 | 0.77 | ADORA3 (1.00) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL29573781 | 0.76 | HTR2B (0.73) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL29574509 | 0.75 | ADORA3 (0.52) | ADORA3ADORA1HTR2BHTR2CTMIGD3 | |
| SCHEMBL6818080 | 0.73 | ADORA3 (0.61) | ADORA3ADORA1ADORA2A | |
| SCHEMBL19464941 | 0.72 | HTR2B (1.00) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL19464934 | 0.72 | HTR2B (1.00) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL19464867 | 0.72 | HTR2B (1.00) | ADORA3ADORA1HTR2BHTR2CADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457356-A | A3 adenosine receptor agonists for use in medicine | 生物干预公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-4196219-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | Biointervene, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022040241-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | BIOINTERVENE, INC. (US) | 2022-02-24 | — | — | WO | disclosed |